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Synthesis of Protectin D1 Analogs: Novel Pro-resolution and Radiotracer Agents

Protectin D1 is a specialized pro-resolving mediator with potent pro-resolving and anti-inflammatory effects in vivo in several human disease models. Herein the preparation of the first synthetic analog of protectin D1, named 22-F-PD1, is presented together with data from in vivo investigations. Thi...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Org Biomol Chem
Main Authors: Tungen, J. E., Aursnes, M., Ramon, S., Colas, R. A., Serhan, C. N., Olberg, D. E., Nuruddin, S., Willoch, F., Hansen, T. V.
Format: Artigo
Jezik:Inglês
Izdano: 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6309860/
https://ncbi.nlm.nih.gov/pubmed/30204204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8ob01232f
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