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Stereoselective synthesis of protectin D1: A potent anti-inflammatory and proresolving lipid mediator
A convergent stereoselective synthesis of the potent anti-inflammatory, proresolving and neuroprotective lipid mediator protectin D1 (2) has been achieved in 15% yield over eight steps. The key features were a stereocontrolled Evans-aldol reaction with Nagao’s chiral auxiliary and a highly selective...
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| Hlavní autoři: | , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2013
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3904955/ https://ncbi.nlm.nih.gov/pubmed/24253202 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c3ob41902a |
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