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Synthesis and Anti-inflammatory and Pro-resolving Activities of 22-OH-PD1, a Monohydroxylated Metabolite of Protectin D1

[Image: see text] Protectin D1 (PD1 (3)), a C22-dihydroxylated polyunsaturated fatty acid biosynthesized from all-Z-docosahexaenoic acid, belongs to the new family of endogenous mediators referred to as specialized pro-resolving lipid mediators. PD1 (3) is a natural product that displays potent anti...

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Detalhes bibliográficos
Main Authors: Tungen, Jørn E., Aursnes, Marius, Vik, Anders, Ramon, Sesquile, Colas, Romain A., Dalli, Jesmond, Serhan, Charles N., Hansen, Trond V.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society and American Society of Pharmacognosy 2014
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4208671/
https://ncbi.nlm.nih.gov/pubmed/25247845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/np500498j
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