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Electrochemical measurement of membrane cholesterol correlates with CFTR function and is HDAC6-dependent

BACKGROUND: Previous studies have demonstrated that CF epithelial cells exhibit increased cholesterol content at the plasma membrane compared to wild type controls as measured by electrochemical methods. Microtubule dysregulation that impacts intracellular transport has also been identified in CF ce...

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Detalhes bibliográficos
Publicado no:J Cyst Fibros
Main Authors: Lu, Binyu, Li, Li, Schneider, Molly, Hodges, Craig A., Cotton, Calvin U., Burgess, James D., Kelley, Thomas J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6309594/
https://ncbi.nlm.nih.gov/pubmed/29941319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jcf.2018.06.005
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