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Electrochemical measurement of membrane cholesterol correlates with CFTR function and is HDAC6-dependent

BACKGROUND: Previous studies have demonstrated that CF epithelial cells exhibit increased cholesterol content at the plasma membrane compared to wild type controls as measured by electrochemical methods. Microtubule dysregulation that impacts intracellular transport has also been identified in CF ce...

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Dettagli Bibliografici
Pubblicato in:J Cyst Fibros
Autori principali: Lu, Binyu, Li, Li, Schneider, Molly, Hodges, Craig A., Cotton, Calvin U., Burgess, James D., Kelley, Thomas J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6309594/
https://ncbi.nlm.nih.gov/pubmed/29941319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jcf.2018.06.005
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