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Cellular localization of PD-L1 expression in mismatch repair-deficient and proficient colorectal carcinomas.

Blockade of the interaction between PD-1 and its ligands (PD-L1 and PD-L2) has shown clinical efficacy across several tumor types, especially in mismatch-repair-deficient colorectal carcinoma. The aim of this study was to examine the pattern and cellular localization of PD-L1 expression in the diffe...

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Detalhes bibliográficos
Publicado no:Mod Pathol
Main Authors: Liu, Sandy, Gӧnen, Mithat, Stadler, Zsofia K., Weiser, Martin R., Hechtman, Jaclyn F., Vakiani, Efsevia, Wang, Tao, Vyas, Monika, Joneja, Upasana, Al-Bayati, Moataz, Segal, Neil H., Smith, J. Joshua, King, Sarah, Guercio, Shanna, Ntiamoah, Peter, Markowitz, Arnold J., Zhang, Liying, Cercek, Andrea, Garcia-Aguilar, Julio, Saltz, Leonard B., Diaz, Luis A., Klimstra, David S., Shia, Jinru
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6309293/
https://ncbi.nlm.nih.gov/pubmed/30166615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41379-018-0114-7
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