Patterns and prognostic relevance of PD-1 and PD-L1 expression in colorectal carcinoma

Immune checkpoint blockade targeting the programmed death-1 (PD-1) pathway has shown efficacy in several types of cancers including mismatch-repair-deficient colorectal carcinoma. In some tumor types, programmed death-ligand 1 (PD-L1) expression detected by immunohistochemistry has shown utility as...

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Detalhes bibliográficos
Publicado no:Mod Pathol
Main Authors: Lee, Lik Hang, Cavalcanti, Marcela S, Segal, Neil H, Hechtman, Jaclyn F, Weiser, Martin R, Smith, J Joshua, Garcia-Aguilar, Julio, Sadot, Eran, Ntiamoah, Peter, Markowitz, Arnold J, Shike, Moshe, Stadler, Zsofia K, Vakiani, Efsevia, Klimstra, David S, Shia, Jinru
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5083129/
https://ncbi.nlm.nih.gov/pubmed/27443512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/modpathol.2016.139
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