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ADAR2-mediated Q/R editing of GluK2 regulates kainate receptor upscaling in response to suppression of synaptic activity

Kainate receptors (KARs) regulate neuronal excitability and network function. Most KARs contain the subunit GluK2 (also known as GRIK2), and the properties of these receptors are determined in part by ADAR2 (also known as ADARB1)-mediated mRNA editing of GluK2, which changes a genomically encoded gl...

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Detalhes bibliográficos
Publicado no:J Cell Sci
Main Authors: Gurung, Sonam, Evans, Ashley J., Wilkinson, Kevin A., Henley, Jeremy M.
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6307878/
https://ncbi.nlm.nih.gov/pubmed/30559217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.222273
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