Impact of central and peripheral estrogen treatment on anxiety and depression phenotypes in a mouse model of postmenopausal obesity

Obesity and diabetes increase the risk of depression, and the incidence of these conditions increases rapidly after menopause, but few animal models of postmenopausal obesity have been available. We developed a mouse model of postmenopausal obesity that exhibited anxiety and depressive phenotypes in...

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Dettagli Bibliografici
Pubblicato in:PLoS One
Autori principali: Wada, Tsutomu, Sameshima, Azusa, Yonezawa, Rika, Morita, Mayuko, Sawakawa, Kanae, Tsuneki, Hiroshi, Sasaoka, Toshiyasu, Saito, Shigeru
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2018
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6307752/
https://ncbi.nlm.nih.gov/pubmed/30589890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0209859
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