Impact of central and peripheral estrogen treatment on anxiety and depression phenotypes in a mouse model of postmenopausal obesity

Obesity and diabetes increase the risk of depression, and the incidence of these conditions increases rapidly after menopause, but few animal models of postmenopausal obesity have been available. We developed a mouse model of postmenopausal obesity that exhibited anxiety and depressive phenotypes in...

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Udgivet i:PLoS One
Main Authors: Wada, Tsutomu, Sameshima, Azusa, Yonezawa, Rika, Morita, Mayuko, Sawakawa, Kanae, Tsuneki, Hiroshi, Sasaoka, Toshiyasu, Saito, Shigeru
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2018
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6307752/
https://ncbi.nlm.nih.gov/pubmed/30589890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0209859
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