Novel Role for PD-1:PD-L1 as Mediator of Pulmonary Vascular Endothelial Cell Functions in Pathogenesis of Indirect ARDS in Mice

Deficiency of the co-inhibitory receptor, Programmed cell death receptor (PD)-1, provides a survival benefit in our murine shock/sepsis model for the development of indirect acute respiratory distress syndrome (iARDS). Further, of clinical significance, patients that develop ARDS express increased P...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Lomas-Neira, Joanne, Monaghan, Sean F., Huang, Xin, Fallon, Eleanor A., Chung, Chun-Shiang, Ayala, Alfred
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6306416/
https://ncbi.nlm.nih.gov/pubmed/30619369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.03030
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