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Active players in resolution of shock/sepsis induced indirect lung injury: immunomodulatory effects of T(regs) and PD-1

The immunomodulatory effects of PD-1 and CD4(+)CD25(+) T(regs) in the resolution of ALI are still poorly understood. Accordingly, 1 million T(regs) were isolated from spleens of WT C57BL/6 or PD-1(−/−) mice (magnetical bead purification and subsequent labeling with/without Vybrant dye) and then AT i...

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Detalhes bibliográficos
Main Authors: Tang, Lunxian, Bai, Jianwen, Chung, Chun-Shiang, Lomas-Neira, Joanne, Chen, Yaping, Huang, Xin, Ayala, Alfred
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Leukocyte Biology 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4197571/
https://ncbi.nlm.nih.gov/pubmed/25082151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.4MA1213-647RR
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