PD-L1 regulates the Tregs’ capacity to repress shock/sepsis induced indirect lung injury (iALI) by recruiting phosphatase SHP-1

We recently reported that adoptively transferred (AT) exogenous CD4(+)CD25(+) regulatory T cells (Tregs) to wild type (WT) mice can directly act to repress shock/sepsis induced experimental iALI and this is mediated in part by programmed cell death receptor 1 (PD-1). In this study, we further determ...

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Detalhes bibliográficos
Publicado no:Shock
Main Authors: Tang, Lunxian, Bai, Jianwen, Chung, Chun-Shiang, Lomas–Neira, Joanne, Chen, Yaping, Huang, Xin, Ayala, Alfred
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4269554/
https://ncbi.nlm.nih.gov/pubmed/25057927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/SHK.0000000000000247
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