Evaluation of the antifibrotic potency by knocking down SPARC, CCR2 and SMAD3

BACKGROUND: The genes of SPARC, CCR2, and SMAD3 are implicated in orchestrating inflammatory response that leads to fibrosis in scleroderma and other fibrotic disorders. The aim of the studies is to evaluate synergistic anti-fibrotic potency of the siRNAs of these genes. METHODS: The efficacy of the...

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Dades bibliogràfiques
Publicat a:EBioMedicine
Autors principals: Ding, Weifeng, Pu, Weilin, Jiang, Shuai, Ma, Yanyun, Liu, Qingmei, Wu, Wenyu, Chu, Haiyan, Zou, Hejian, Jin, Li, Wang, Jiucun, Zhou, Xiaodong
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2018
Matèries:
Research paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6306344/
https://ncbi.nlm.nih.gov/pubmed/30470612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2018.11.016
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