Involvement of collagen-binding heat shock protein 47 in scleroderma-associated fibrosis

Uncontrolled fibrosis of skin and internal organs is the main characteristic of scleroderma, and collagen is a major extracellular matrix protein that deposits in the fibrotic organs. As the chaperone of collagen, heat shock protein 47 (HSP47) is closely related with the development of fibrosis. To...

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Bibliographic Details
Published in:Protein Cell
Main Authors: Chu, Haiyan, Wu, Ting, Wu, Wenyu, Tu, Wenzhen, Jiang, Shuai, Chen, Sidi, Ma, Yanyun, Liu, Qingmei, Zhou, Xiaodong, Jin, Li, Wang, Jiucun
Format: Artigo
Language:Inglês
Published: Higher Education Press 2015
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4506285/
https://ncbi.nlm.nih.gov/pubmed/26091621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13238-015-0171-3
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