Clonal analysis of HIV-1 genotype and function associated with virologic failure in treatment-experienced persons receiving maraviroc: Results from the MOTIVATE phase 3 randomized, placebo-controlled trials

Detailed clonal phenotypic/genotypic analyses explored viral-escape mechanisms during maraviroc-based therapy in highly treatment-experienced participants from the MOTIVATE trials. To allow real-time assessment of samples while maintaining a blind trial, the first 267 enrolled participants were sele...

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Publicat a:PLoS One
Autors principals: Lewis, Marilyn, Mori, Julie, Toma, Jonathan, Mosley, Mike, Huang, Wei, Simpson, Paul, Mansfield, Roy, Craig, Charles, van der Ryst, Elna, Robertson, David L., Whitcomb, Jeannette M., Westby, Mike
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2018
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6306210/
https://ncbi.nlm.nih.gov/pubmed/30586365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0204099
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