Spotlight on dinutuximab in the treatment of high-risk neuroblastoma: development and place in therapy

Neuroblastoma (NB) is a pediatric cancer of the sympathetic nervous system which accounts for 8% of childhood cancers. Most NBs express high levels of the disialoganglioside GD2. Several antibodies have been developed to target GD2 on NB, including the human/mouse chimeric antibody ch14.18, known as...

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Bibliografiske detaljer
Udgivet i:Biologics
Main Authors: Keyel, Michelle E, Reynolds, C Patrick
Format: Artigo
Sprog:Inglês
Udgivet: Dove Medical Press 2018
Fag:
Review
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6306059/
https://ncbi.nlm.nih.gov/pubmed/30613134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/BTT.S114530
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