Spotlight on ceritinib in the treatment of ALK+ NSCLC: design, development and place in therapy

The identification of echinoderm microtubule-associated protein-like 4 (EML4) and anaplastic lymphoma kinase (ALK) fusion gene in non-small cell lung cancer (NSCLC) has radically changed the treatment of a subset of patients harboring this oncogenic driver. Crizotinib was the first ALK tyrosine kina...

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Detalhes bibliográficos
Publicado no:Drug Des Devel Ther
Main Authors: Santarpia, Mariacarmela, Daffinà, Maria Grazia, D’Aveni, Alessandro, Marabello, Grazia, Liguori, Alessia, Giovannetti, Elisa, Karachaliou, Niki, Gonzalez Cao, Maria, Rosell, Rafael, Altavilla, Giuseppe
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2017
Assuntos:
Review
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5503498/
https://ncbi.nlm.nih.gov/pubmed/28740365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S113500
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