Effects of APOE Genotype on Brain Proteomic Network and Cell Type Changes in Alzheimer's Disease

Polymorphic alleles in the apolipoprotein E (APOE) gene are the main genetic determinants of late-onset Alzheimer's disease (AD) risk. Individuals carrying the APOE E4 allele are at increased risk to develop AD compared to those carrying the more common E3 allele, whereas those carrying the E2...

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Detalhes bibliográficos
Publicado no:Front Mol Neurosci
Main Authors: Dai, Jingting, Johnson, Erik C. B., Dammer, Eric B., Duong, Duc M., Gearing, Marla, Lah, James J., Levey, Allan I., Wingo, Thomas S., Seyfried, Nicholas T.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6305300/
https://ncbi.nlm.nih.gov/pubmed/30618606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2018.00454
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