A proteomic network approach across the ALS‐FTD disease spectrum resolves clinical phenotypes and genetic vulnerability in human brain

Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) are neurodegenerative diseases with overlap in clinical presentation, neuropathology, and genetic underpinnings. The molecular basis for the overlap of these disorders is not well established. We performed a comparative unbiased m...

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Detalhes bibliográficos
Publicado no:EMBO Mol Med
Main Authors: Umoh, Mfon E, Dammer, Eric B, Dai, Jingting, Duong, Duc M, Lah, James J, Levey, Allan I, Gearing, Marla, Glass, Jonathan D, Seyfried, Nicholas T
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5760858/
https://ncbi.nlm.nih.gov/pubmed/29191947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.201708202
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