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Folate deficiency drives mitotic missegregation of the human FRAXA locus
The instability of chromosome fragile sites is implicated as a causative factor in several human diseases, including cancer [for common fragile sites (CFSs)] and neurological disorders [for rare fragile sites (RFSs)]. Previous studies have indicated that problems arising during DNA replication are t...
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| Опубликовано в: : | Proc Natl Acad Sci U S A |
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| Главные авторы: | , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
National Academy of Sciences
2018
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6304931/ https://ncbi.nlm.nih.gov/pubmed/30509972 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1808377115 |
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