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Prediction of deleterious mutations in coding regions of mammals with transfer learning

The genomes of mammals contain thousands of deleterious mutations. It is important to be able to recognize them with high precision. In conservation biology, the small size of fragmented populations results in accumulation of damaging variants. Preserving animals with less damaged genomes could opti...

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Detalhes bibliográficos
Publicado no:Evol Appl
Main Authors: Plekhanova, Elena, Nuzhdin, Sergey V., Utkin, Lev V., Samsonova, Maria G.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6304693/
https://ncbi.nlm.nih.gov/pubmed/30622632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/eva.12607
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