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Accumulation of slightly deleterious mutations in mitochondrial protein-coding genes of large versus small mammals
After the effective size of a population, N(e), declines, some slightly deleterious amino acid replacements which were initially suppressed by purifying selection become effectively neutral and can reach fixation. Here we investigate this phenomenon for a set of all 13 mitochondrial protein-coding g...
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| 主要な著者: | , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
National Academy of Sciences
2007
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1948928/ https://ncbi.nlm.nih.gov/pubmed/17679693 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0701256104 |
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