Droplet digital PCR for the quantification of Alu methylation status in hematological malignancies

BACKGROUND: Alu repeats, belonging to the Short Interspersed Repetitive Elements (SINEs) class, contain about 25% of CpG sites in the human genome. Alu sequences lie in gene-rich regions, so their methylation is an important transcriptional regulation mechanism. Aberrant Alu methylation has been ass...

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Dades bibliogràfiques
Publicat a:Diagn Pathol
Autors principals: Orsini, Paola, Impera, Luciana, Parciante, Elisa, Cumbo, Cosimo, Minervini, Crescenzio F., Minervini, Angela, Zagaria, Antonella, Anelli, Luisa, Coccaro, Nicoletta, Casieri, Paola, Tota, Giuseppina, Brunetti, Claudia, Ricco, Alessandra, Carluccio, Paola, Specchia, Giorgina, Albano, Francesco
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2018
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6303857/
https://ncbi.nlm.nih.gov/pubmed/30579366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13000-018-0777-x
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