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Active Site Breathing of Human Alkbh5 Revealed by Solution NMR and Accelerated Molecular Dynamics
AlkB homolog 5 (Alkbh5) is one of nine members of the AlkB family, which are nonheme Fe(2+)/α-ketoglutarate-dependent dioxygenases that catalyze the oxidative demethylation of modified nucleotides and amino acids. Alkbh5 is highly selective for the N(6)-methyladenosine modification, an epigenetic ma...
Gorde:
| Argitaratua izan da: | Biophys J |
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| Egile Nagusiak: | , , , , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
The Biophysical Society
2018
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6303414/ https://ncbi.nlm.nih.gov/pubmed/30352661 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2018.10.004 |
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