Loss of Phd2 cooperates with BRAF(V600E) to drive melanomagenesis

Prolyl hydroxylase domain protein 2 (PHD2) is a well-known master oxygen sensor. However, the role of PHD2 in tumor initiation remains controversial. We find that during the transition of human nevi to melanoma, the expression of PHD2 protein is significantly decreased and lower expression PHD2 in m...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Nat Commun
Autors principals: Liu, Shujing, Zhang, Gao, Guo, Jianping, Chen, Xiang, Lei, Jingce, Ze, Kan, Dong, Liyun, Dai, Xiangpeng, Gao, Yang, Song, Daisheng, Ecker, Brett L., Yang, Ruifeng, Feltcher, Caitlin, Peng, Kai, Feng, Cheng, Chen, Hui, Lee, Rebecca X., Kerestes, Heddy, Niu, Jingwen, Kumar, Suresh, Xu, Weiting, Zhang, Jie, Wei, Zhi, Martin, James S., Liu, Xiaoming, Mills, Gordon, Lu, Yiling, Guo, Wei, Sun, Lunquan, Zhang, Lin, Weeraratna, Ashani, Herlyn, Meenhard, Wei, Wenyi, Lee, Frank S., Xu, Xiaowei
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2018
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6303344/
https://ncbi.nlm.nih.gov/pubmed/30575721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-07126-9
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars