Centromere DNA Destabilizes H3 Nucleosomes to Promote CENP-A Deposition during the Cell Cycle

Active centromeres are defined by the presence of nucleosomes containing CENP-A, a histone H3 variant, which alone is sufficient to direct kinetochore assembly. Once assembled at a location, CENP-A chromatin and kinetochores are maintained at that location through a positive feedback loop where kine...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Curr Biol
Main Authors: Shukla, Manu, Tong, Pin, White, Sharon A., Singh, Puneet P., Reid, Angus M., Catania, Sandra, Pidoux, Alison L., Allshire, Robin C.
Format: Artigo
Sprog:Inglês
Udgivet: Cell Press 2018
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6303189/
https://ncbi.nlm.nih.gov/pubmed/30503616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2018.10.049
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker