PremPDI estimates and interprets the effects of missense mutations on protein-DNA interactions

Protein-DNA interactions play important roles in regulations of many vital cellular processes, including transcription, translation, DNA replication and recombination. Sequence variants occurring in these DNA binding proteins that alter protein-DNA interactions may cause significant perturbations or...

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Udgivet i:PLoS Comput Biol
Main Authors: Zhang, Ning, Chen, Yuting, Zhao, Feiyang, Yang, Qing, Simonetti, Franco L., Li, Minghui
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2018
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6303081/
https://ncbi.nlm.nih.gov/pubmed/30533007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1006615
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