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Automated in situ chromatin profiling efficiently resolves cell types and gene regulatory programs

BACKGROUND: Our understanding of eukaryotic gene regulation is limited by the complexity of protein–DNA interactions that comprise the chromatin landscape and by inefficient methods for characterizing these interactions. We recently introduced CUT&RUN, an antibody-targeted nuclease cleavage meth...

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التفاصيل البيبلوغرافية
الحاوية / القاعدة:	Epigenetics Chromatin
المؤلفون الرئيسيون:	Janssens, Derek H., Wu, Steven J., Sarthy, Jay F., Meers, Michael P., Myers, Carrie H., Olson, James M., Ahmad, Kami, Henikoff, Steven
التنسيق:	Artigo
اللغة:	Inglês
منشور في:	BioMed Central 2018
الموضوعات:	Methodology
الوصول للمادة أونلاين:	https://ncbi.nlm.nih.gov/pmc/articles/PMC6302505/ https://ncbi.nlm.nih.gov/pubmed/30577869 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13072-018-0243-8
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Automated in situ chromatin profiling efficiently resolves cell types and gene regulatory programs

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