The molecular basis of protein toxin HicA–dependent binding of the protein antitoxin HicB to DNA

Toxin–antitoxin (TA) systems are present in many bacteria and play important roles in bacterial growth, physiology, and pathogenicity. Those that are best studied are the type II TA systems, in which both toxins and antitoxins are proteins. The HicAB system is one of the prototypic TA systems, found...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Winter, Ashley J., Williams, Christopher, Isupov, Michail N., Crocker, Hannah, Gromova, Mariya, Marsh, Philip, Wilkinson, Oliver J., Dillingham, Mark S., Harmer, Nicholas J., Titball, Richard W., Crump, Matthew P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2018
Assuntos:
Microbiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6302177/
https://ncbi.nlm.nih.gov/pubmed/30337369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.005173
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