The HicA toxin from Burkholderia pseudomallei has a role in persister cell formation

TA (toxin–antitoxin) systems are widely distributed amongst bacteria and are associated with the formation of antibiotic tolerant (persister) cells that may have involvement in chronic and recurrent disease. We show that overexpression of the Burkholderia pseudomallei HicA toxin causes growth arrest...

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Autori principali: Butt, Aaron, Higman, Victoria A., Williams, Christopher, Crump, Matthew P., Hemsley, Claudia M., Harmer, Nicholas, Titball, Richard W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Portland Press Ltd. 2014
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3969222/
https://ncbi.nlm.nih.gov/pubmed/24502667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20140073
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