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A Polymer Model for the Quantitative Reconstruction of Chromosome Architecture from HiC and GAM Data

It is widely believed that the folding of the chromosome in the nucleus has a major effect on genetic expression. For example, coregulated genes in several species have been shown to colocalize in space despite being far away on the DNA sequence. In this manuscript, we present a new, to our knowledg...

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Detalhes bibliográficos
Publicado no:Biophys J
Main Authors: Le Treut, Guillaume, Képès, François, Orland, Henri
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6301988/
https://ncbi.nlm.nih.gov/pubmed/30527448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2018.10.032
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