RNF138 confers cisplatin resistance in gastric cancer cells via activating Chk1 signaling pathway

Chemotherapy resistance represents a major issue associated with gastric cancer (GC) treatment, and arises through multiple mechanisms, including modulation of the cell-cycle check point. Several ubiquitin kinases, including RING finger protein 138 (RNF138), have been reported to mediate the G2/M ph...

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Veröffentlicht in:Cancer Biol Ther
Hauptverfasser: Lu, Yalan, Han, Deqiang, Liu, Wenjie, Huang, Rong, Ou, Jinhuan, Chen, Xiaoqiao, Zhang, Xizhe, Wang, Xuezhi, Li, Shijun, Wang, Lin, Liu, Changzheng, Miao, Shiying, Wang, Linfang, Ma, Changwu, Song, Wei
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis 2018
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6301830/
https://ncbi.nlm.nih.gov/pubmed/30260263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384047.2018.1480293
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