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Identification of Common and Rare Genetic Variation Associated with Plasma Protein Levels using Whole Exome Sequencing and Mass Spectrometry

BACKGROUND: Identifying genetic variation associated with plasma protein levels, and the mechanisms by which they act, could provide insight into alterable processes involved in regulation of protein levels. While protein levels can be affected by genetic variants, their estimation can also be biase...

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Detalhes bibliográficos
Publicado no:Circ Genom Precis Med
Main Authors: Solomon, Terry, Lapek, John D., Jensen, Søren Beck, Greenwald, William W, Hindberg, Kristian, Matsui, Hiroko, Latysheva, Nadezhda, Braekken, Sigrid K, Gonzalez, David J, Frazer, Kelly A, Smith, Erin N, Hansen, John-Bjarne
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6301071/
https://ncbi.nlm.nih.gov/pubmed/30562114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCGEN.118.002170
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