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Associations Between Common and Rare Exonic Genetic Variants and Serum Levels of 20 Cardiovascular-Related Proteins: The Tromsø Study

BACKGROUND—: Genetic variation can be used to study causal relationships between biomarkers and diseases. Here, we identify new common and rare genetic variants associated with cardiovascular-related protein levels (protein quantitative trait loci [pQTLs]). We functionally annotate these pQTLs, pred...

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Detalhes bibliográficos
Publicado no:Circ Cardiovasc Genet
Main Authors: Solomon, Terry, Smith, Erin N., Matsui, Hiroko, Braekkan, Sigrid K., Wilsgaard, Tom, Njølstad, Inger, Mathiesen, Ellisiv B., Hansen, John-Bjarne, Frazer, Kelly A.
Formato: Artigo
Idioma:Inglês
Publicado em: Lippincott Williams & Wilkins 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4982757/
https://ncbi.nlm.nih.gov/pubmed/27329291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCGENETICS.115.001327
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