Hepatic PPARγ and LXRα independently regulate lipid accumulation in the livers of genetically obese mice

The nuclear hormone receptors liver X receptor α (LXRα) and peroxisome proliferator-activated receptor γ (PPARγ) play key roles in the development of fatty liver. To determine the link between hepatic PPARγ and LXRα signaling and the development of fatty liver, a LXRα-specific ligand, T0901317, was...

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Bibliographic Details
Published in:FEBS Lett
Main Authors: Matsusue, Kimihiko, Aibara, Daisuke, Hayafuchi, Risa, Matsuo, Kohei, Takiguchi, Soichi, Gonzalez, Frank J., Yamano, Shigeru
Format: Artigo
Language:Inglês
Published: 2014
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6301023/
https://ncbi.nlm.nih.gov/pubmed/24857376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2014.05.012
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