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Single-Cell Transcriptomes Distinguish Stem Cell State Changes and Lineage Specification Programs in Early Mammary Gland Development

The mammary gland consists of cells with gene expression patterns reflecting their cellular origins, function, and spatiotemporal context. However, knowledge of developmental kinetics and mechanisms of lineage specification is lacking. We address this significant knowledge gap by generating a single...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Giraddi, Rajshekhar R., Chung, Chi-Yeh, Heinz, Richard E., Balcioglu, Ozlen, Novotny, Mark, Trejo, Christy L., Dravis, Christopher, Hagos, Berhane M., Mehrabad, Elnaz Mirzaei, Rodewald, Luo Wei, Hwang, Jae Y., Fan, Cheng, Lasken, Roger, Varley, Katherine E., Perou, Charles M., Wahl, Geoffrey M., Spike, Benjamin T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6301014/
https://ncbi.nlm.nih.gov/pubmed/30089273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2018.07.025
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