Improved Method for Determining Absolute Phosphorylation Stoichiometry Using Bayesian Statistics and Isobaric Labeling

[Image: see text] Phosphorylation stoichiometry, or occupancy, is one element of phosphoproteomics that can add useful biological context (Gerber et al. Proc. Natl. Acad. Sci. U. S. A. 2003, 100, 6940–5). We previously developed a method to assess phosphorylation stoichiometry on a proteome-wide sca...

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Bibliographic Details
Published in:J Proteome Res
Main Authors: Lim, Matthew Y., O’Brien, Jonathon, Paulo, Joao A., Gygi, Steven P.
Format: Artigo
Language:Inglês
Published: 2017
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6301010/
https://ncbi.nlm.nih.gov/pubmed/28985074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jproteome.7b00571
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