The Pneumococcal Surface Proteins PspA and PspC Sequester Host C4-Binding Protein To Inactivate Complement C4b on the Bacterial Surface

Complement is a critical component of antimicrobial immunity. Various complement regulatory proteins prevent host cells from being attacked. Many pathogens have acquired the ability to sequester complement regulators from host plasma to evade complement attack. We describe here how Streptococcus pne...

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Detalles Bibliográficos
Publicado en:Infect Immun
Main Authors: Haleem, Kashif S., Ali, Youssif M., Yesilkaya, Hasan, Kohler, Thomas, Hammerschmidt, Sven, Andrew, Peter W., Schwaeble, Wilhelm J., Lynch, Nicholas J.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2018
Assuntos:
Host Response and Inflammation
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6300637/
https://ncbi.nlm.nih.gov/pubmed/30323030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00742-18
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