PspC, a Pneumococcal Surface Protein, Binds Human Factor H

PspC was found to bind human complement factor H (FH) by Western blot analysis of D39 (pspC(+)) and an isogenic mutant TRE108 (pspC). We confirmed that PspA does not bind FH, while purified PspC binds FH very strongly. The binding of FH to exponentially growing pneumococci varied among different iso...

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Detalhes bibliográficos
Main Authors: Dave, Sandhya, Brooks-Walter, Alexis, Pangburn, Michael K., McDaniel, Larry S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC98306/
https://ncbi.nlm.nih.gov/pubmed/11292770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.69.5.3435-3437.2001
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