Targeting B7-H1 (PD-L1) sensitizes cancer cells to chemotherapy

Development of resistance to chemotherapy is a major obstacle in extending the survival of patients with cancer. Although originally defined as an immune checkpoint molecule, B7-H1 (also named as PD-L1 or CD274) was found to play a role in cancer chemoresistance; however, the underlying mechanism of...

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Detalhes bibliográficos
Publicado no:Heliyon
Main Authors: Wu, Xiaosheng, Li, Yanli, Liu, Xin, Chen, Chunhua, Harrington, Susan M., Cao, Siyu, Xie, Tiancheng, Pham, Tu, Mansfield, Aaron S., Yan, Yiyi, Kwon, Eugene D., Wang, Liewei, Ling, Kun, Dong, Haidong
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6300616/
https://ncbi.nlm.nih.gov/pubmed/30603685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.heliyon.2018.e01039
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