Nintedanib inhibits TGF-β-induced myofibroblast transdifferentiation in human Tenon’s fibroblasts

PURPOSE: This study aimed to investigate the effect of nintedanib on the conversion of human Tenon’s fibroblasts (HTFs) into myofibroblasts and reveal the molecular mechanisms involved. METHODS: Primary cultured HTFs were incubated with transforming growth factor β1 (TGF-β1) alone or combined with n...

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Veröffentlicht in:Mol Vis
Hauptverfasser: Lin, Xianchai, Wen, Jiamin, Liu, Rongjiao, Gao, Wuyou, Qu, Bo, Yu, Minbin
Format: Artigo
Sprache:Inglês
Veröffentlicht: Molecular Vision 2018
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6300612/
https://ncbi.nlm.nih.gov/pubmed/30636861
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