Genetic Ancestry Markers and Difference in A1c Between African American and White in the Diabetes Prevention Program

PURPOSE: HbA1c levels are higher in blacks than non-Hispanic whites (NHWs). We investigated whether genetics could explain this difference in Diabetes Prevention Program (DPP) participants. METHODS: We tested (i) genetic variants causing hemoglobinopathies, (ii) a genetic risk score (GRS) based on 6...

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Vydáno v:J Clin Endocrinol Metab
Hlavní autoři: Hivert, Marie-France, Christophi, Costas A, Jablonski, Kathleen A, Edelstein, Sharon L, Kahn, Steven E, Golden, Sherita Hill, Dagogo-Jack, Samuel, Mather, Kieren J, Luchsinger, José A, Caballero, A Enrique, Barrett-Connor, Elizabeth, Knowler, William C, Florez, Jose C, Herman, William H
Médium: Artigo
Jazyk:Inglês
Vydáno: Endocrine Society 2018
Témata:
Clinical Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6300069/
https://ncbi.nlm.nih.gov/pubmed/30358859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2018-01416
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