The C Allele of ATM rs11212617 Does Not Associate With Metformin Response in the Diabetes Prevention Program

OBJECTIVE: The C allele at the rs11212617 polymorphism in the ataxia-telangiectasia–mutated (ATM) gene has been associated with greater clinical response to metformin in people with type 2 diabetes. We tested whether this variant modified the effect of metformin in the Diabetes Prevention Program (D...

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Autors principals: Florez, Jose C., Jablonski, Kathleen A., Taylor, Andrew, Mather, Kieren, Horton, Edward, White, Neil H., Barrett-Connor, Elizabeth, Knowler, William C., Shuldiner, Alan R., Pollin, Toni I.
Format: Artigo
Idioma:Inglês
Publicat: American Diabetes Association 2012
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Original Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3425006/
https://ncbi.nlm.nih.gov/pubmed/22751958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/dc11-2301
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