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Genetic Modulation of Lipid Profiles following Lifestyle Modification or Metformin Treatment: The Diabetes Prevention Program

Weight-loss interventions generally improve lipid profiles and reduce cardiovascular disease risk, but effects are variable and may depend on genetic factors. We performed a genetic association analysis of data from 2,993 participants in the Diabetes Prevention Program to test the hypotheses that a...

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Detalhes bibliográficos
Main Authors: Pollin, Toni I., Isakova, Tamara, Jablonski, Kathleen A., de Bakker, Paul I. W., Taylor, Andrew, McAteer, Jarred, Pan, Qing, Horton, Edward S., Delahanty, Linda M., Altshuler, David, Shuldiner, Alan R., Goldberg, Ronald B., Florez, Jose C., Franks, Paul W.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3431328/
https://ncbi.nlm.nih.gov/pubmed/22951888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1002895
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