SFXN1 is a mitochondrial serine transporter required for one-carbon metabolism

One-carbon metabolism generates the one-carbon units required to synthesize many critical metabolites, including nucleotides. The pathway has cytosolic and mitochondrial branches, and a key step is the entry, through an unknown mechanism, of serine into mitochondria, where it is converted into glyci...

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Udgivet i:Science
Main Authors: Kory, Nora, Wyant, Gregory A., Prakash, Gyan, de Bos, Jelmi uit, Bottanelli, Francesca, Pacold, Michael E., Chan, Sze Ham, Lewis, Caroline A., Wang, Tim, Keys, Heather R., Guo, Yang Eric, Sabatini, David M.
Format: Artigo
Sprog:Inglês
Udgivet: 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6300058/
https://ncbi.nlm.nih.gov/pubmed/30442778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aat9528
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