Exploring the genetic basis of human population differences in DNA methylation and their causal impact on immune gene regulation

BACKGROUND: DNA methylation is influenced by both environmental and genetic factors and is increasingly thought to affect variation in complex traits and diseases. Yet, the extent of ancestry-related differences in DNA methylation, their genetic determinants, and their respective causal impact on im...

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Dettagli Bibliografici
Pubblicato in:Genome Biol
Autori principali: Husquin, Lucas T., Rotival, Maxime, Fagny, Maud, Quach, Hélène, Zidane, Nora, McEwen, Lisa M., MacIsaac, Julia L., Kobor, Michael S., Aschard, Hugues, Patin, Etienne, Quintana-Murci, Lluis
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2018
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6299574/
https://ncbi.nlm.nih.gov/pubmed/30563547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-018-1601-3
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