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Applications of CRISPR-Cas Enzymes in Cancer Therapeutics and Detection

Cancer is a complex disease caused by combinations of cellular genetic alterations and heterogeneous microenvironments. The use of the robust and programmable CRISPR-Cas systems has greatly improved genome editing for precision cancer modeling and enabled multiplexed genetic manipulation for cancer...

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Detalhes bibliográficos
Publicado no:Trends Cancer
Main Authors: Huang, Chun-Hao, Lee, Ko-Chuan, Doudna, Jennifer A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6299457/
https://ncbi.nlm.nih.gov/pubmed/29937048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.trecan.2018.05.006
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