Chromosome 3p Loss–Orchestrated VHL, HIF, and Epigenetic Deregulation in Clear Cell Renal Cell Carcinoma

Clear cell renal cell carcinoma (ccRCC) is the most common renal cell carcinoma subtype, and metastatic ccRCC is associated with 5-year survival rates of 10% to 20%. Genetically, ccRCC originates from sequential losses of multiple tumor suppressor genes. Remarkably, chromosome 3p loss occurs in more...

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:J Clin Oncol
Main Authors: Hsieh, James J., Le, Valerie H., Oyama, Toshinao, Ricketts, Christopher J., Ho, Thai Huu, Cheng, Emily H.
Formato: Artigo
Idioma:Inglês
Publicado: American Society of Clinical Oncology 2018
Assuntos:
Special Series: Kidney Cancer
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6299341/
https://ncbi.nlm.nih.gov/pubmed/30372397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2018.79.2549
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares