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B7-H1 agonists could prevent disseminated inflammation by desensitizing cell susceptibility to cytotoxic T-cells

The B7-H1/PD-1 immune co-inhibitory pathway is functionally bi-directional. We showed previously that B7-H1 could be widely induced on various types of cells and, in addition to be a ligand for PD-1 on T-cells, also serve as an anti-apoptotic receptor upon interacting with PD-1. We explored the role...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Oncoimmunology
Asıl Yazarlar: Yu, Weiwei, Chen, Ling, Guo, Sizheng, Luo, Liqun, Chen, Lieping
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Taylor & Francis 2018
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6298416/
https://ncbi.nlm.nih.gov/pubmed/30574431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2018.1504156
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