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B7-DC (PD-L2) costimulation of CD4(+) T-helper 1 response via RGMb

The role of B7-DC in T-cell responses remains controversial because both coinhibitory and costimulatory functions have been reported in various experimental systems in vitro and in vivo. In addition to interacting with the coinhibitory receptor PD-1, B7-DC has also been shown to bind repulsive guida...

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Detalhes bibliográficos
Publicado no:Cell Mol Immunol
Main Authors: Nie, Xinxin, Chen, Wenni, Zhu, Ying, Huang, Baozhu, Yu, Weiwei, Wu, Zhanshuai, Guo, Sizheng, Zhu, Yiping, Luo, Liqun, Wang, Shengdian, Chen, Lieping
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6207567/
https://ncbi.nlm.nih.gov/pubmed/28479601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cmi.2017.17
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